HUMAN ANTIBODIES AND CONJUGATES OF ANTIBODY-PREPARATION AGAINST CD74 Russian patent published in 2017 - IPC A61K47/50 C07K16/28 A61P35/00 

Abstract RU 2636029 C2

FIELD: biotechnology.

SUBSTANCE: versions of antibodies that bind to human CD74 versions 1 and 2 are presented. A recombinant host cell is provided which generates the said antibody version. Compositions for cancer treatment and prevention containing this antibody version are provided.

EFFECT: group of inventions allows efficient and selective destruction of tumour cells expressing CD74, which can be used in cancer treatment.

55 cl, 15 dwg, 14 tbl, 25 ex

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Authors

Verplugen Sandra

Overdejk Mareje

Dejkkhejzen Rimke Van

Bleker Villem Karel

Berkel Patrik Van

Parren Paul

Lisbyu Sten

Dates

2017-11-17Published

2012-02-01Filed