FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to anhydrous crystalline vinflunine salts of general formula (I) prepared with 1 or 2 equivalents of a pharmaceutically acceptable inorganic or organic acid. . In formula (I) [The acid] represents hydrobromic, lactic or fumaric acid for a group of water-soluble crystalline salts, as well as para-toluenesulphonic, benzoic, mandelic and para-hydroxybenzoic acid for a group of relatively water-insoluble crystalline salts.
EFFECT: preparing the anhydrous crystalline vinflunine salts.
8 cl, 8 ex, 9 dwg
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Authors
Dates
2012-07-20—Published
2008-02-13—Filed