FIELD: chemistry.
SUBSTANCE: disclosed are dodecapeptides of general formula X-Arg(NGY)-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Nle-Pro-Phe-Z, where X=CH3, Y=H, Z-OH for compound (II), X=CH3, Y=H, Z=NH2 for compound (III), X=H, Y=NO2, Z=NH2 for compound (IV), having cardioprotective properties.
EFFECT: disclosed peptides can be used as cardioprotective agents in cardiology for cardiovascular disease therapy.
2 tbl, 4 ex, 1 dwg
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| IMPROVING THE RECOVERY FUNCTION OF THE CARDIOVASCULAR SYSTEM IN ISCHEMIA TETRADECAPEPTIDES | 2017 |
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| DERIVATIVES OF HEMIN AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD FOR PREPARING, APPLICATION AND PHARMACEUTICAL COMPOSITION | 2002 |
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| OCTAPEPTIDE AMIDE, CAPABLE OF RAISING BLOOD PRESSURE AND CARDIAC RATE | 2007 |
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