AMIDE OF NONAPEPTIDE PREVENTING INCREASE OF HYPERPERMEABILITY OF VESSEL ENDOTHELIUM Russian patent published in 2013 - IPC C07K7/06 A61K38/08 A61P7/10 

Abstract RU 2493164 C1

FIELD: biotechnologies.

SUBSTANCE: peptide of the formula H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-D-Arg-Lys-NH2 is proposed. The proposed peptide may find application as an agent for reduction of pathological hyperpermeability of vessel endothelium in various areas of medicine (in cardiology, toxicology, neurosurgery, oncology, etc.).

EFFECT: prevention of sharp increase of vessel endothelium permeability when injected to a recipient.

3 cl, 4 dwg, 1 tbl, 5 ex

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RU 2 493 164 C1

Authors

Abramov Aleksandr Aleksandrovich

Az'Muko Andrej Andreevich

Bespalova Zhanna Dmitrievna

Bushuev Valerij Nikolaevich

Vilitkevich Elena Leonidovna

Kazakova Ol'Ga Alekseevna

Kapel'Ko Valerij Ignat'Evich

Lakomkin Vladimir Leonidovich

Molokoedov Aleksandr Sergeevich

Samsonov Mikhail Vasil'Evich

Sidorova Marija Vladimirovna

Khapchaev Asker Jusufovich

Shirinskij Vladimir Pavlovich

Dates

2013-09-20Published

2012-07-05Filed