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2 457 835

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IPC

A61K31/195(2006-01-01)

A61K9/51(2006-01-01)

A61K9/54(2006-01-01)

B82Y40/00(2011-01-01)

(21) (22)

Application

2011111312/15, 2011-03-25

(24)

Start date

2011-03-25

(22)

Actual filing date

2011-03-25

(45)

Published

2012-08-10

(72)

Inventor

Ivanov Sergej ViktorovichBubelo Vladimir DmitrievichGurov Vjacheslav AlekseevichBarsegjan Gevorkbek GajkovichVorontsov Evgenij AlekseevichKuznetsov Sergej Leonidovich

(73)

Holder

Otkrytoe Aktsionernoe Obshchestvo Proizvodstvennoe Khimiko-Farmatsevticheskoe Ob"Edinenie Im. N.A. Semashko"

GLYCINE-BASED PHARMACEUTICAL COMPOSITION OF PROLONGED ACTION AND METHOD OF ITS OBTAINING Russian patent published in 2012 - IPC A61K31/195 A61K9/51 A61K9/54 B82Y40/00

Abstract RU 2457835 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents pharmaceutical composition of prolonged action which includes non-agglomerated particles, containing active substance glycine and auxiliary substances, characterised by the fact that non-agglomerated particles represent nanoparticles with size from 170 to 500 nm, containing biodegradable polymer, as auxiliary substance polyvinyl alcohol as SAS, poloxamer as stabilising agent and cryoprotectant.

EFFECT: invention ensures increase of bioavailability of active substance glycine resulting from application in composition of biodegradable polymer, due to which coefficient of transmission and glycine assimilability increase, and time of glycine activity in organism grows.

4 cl, 5 ex

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RU 2 457 835 C1

Authors

Ivanov Sergej Viktorovich

Bubelo Vladimir Dmitrievich

Gurov Vjacheslav Alekseevich

Barsegjan Gevorkbek Gajkovich

Vorontsov Evgenij Alekseevich

Kuznetsov Sergej Leonidovich

Dates

2012-08-10—Published

2011-03-25—Filed