FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to veterinary virology and biotechnology, and concerns a cattle viral diarrhoeia vaccine (CVDV). The described vaccine contains an avirulent and purified antigen material of the strain NADL-FGBI "Federal Centre for Animal Health" of the CVDV virus deposited in the collection of Federal State Institution Russian National Centre for Quality and Standartisation of Drugs and Feed for Animals (FGU VGNKI), No. NADL-FGBI "Federal Centre for Animal Health DEP prepared in the passaged mammal cell culture (the passaged cell cultures Taurus-2, PS and RBT) of infectious activity not less than 6,0 lg TCD50/cm3 and ELISA activity not less than 6.6 log2 to inactivation, in the effective amount, and target additives aluminium hydroxide (AHO) and saponin.
EFFECT: presented vaccine shows high antigenic and immunogenic activity and protects the immunised cattle livestock against the homologous CVDV agent.
13 cl, 9 tbl, 7 ex
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Authors
Dates
2012-08-10—Published
2011-01-12—Filed