FIELD: medicine.
SUBSTANCE: strain A(H3N2) - A/8/Perth/16/09 is a reassortant prepared on the basis of two viruses: epidemic A/Perth/16/2009 (H3N2) and high-reproducibility donor A/Puerto Rico/8/34 (H1N1). The strain has inherited the genes HA and NA coding the surface virus proteins from the epidemic virus, and the genes PB1, PB2, PA, NP, M, NS coding the internal non-glycolised proteins from the donor. The strain A(H3N2) - A/8/Perth/16/09 is applicable for production of a monovalent and three-component vaccine for immunisation against influenza virus subtype A(H3N2).
EFFECT: strain shows genetic stability in passages on chicken embryos; it is safe for humans.
3 dwg, 7 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| INFLUENZA VIRUS STRAIN A/Hongkong/1/68/162/35 (H3N2) - UNIVERSAL DONOR OF INTERNAL GENES FOR REASSORTANTS, AND REASSORTANT STRAINS A/SPB/GK/09 (H1N1) AND A/HK/Astana/6:2/2010 (H5N1) PREPARED THEREOF | 2011 |
|
RU2511431C2 |
| RECOMBINANT INFLUENZA VIRUS STRAIN A/PR8/HK-NS80E85A, EXPRESSING FRAGMENTS OF ESAT-6 AND AG85A MYCOBACTERIUM TUBERCULOSIS ANTIGENS, TO OBTAIN TUBERCULOSIS VECTORED VACCINE | 2018 |
|
RU2678175C1 |
| STRAIN OF INFLUENZA VIRUS A/HK/HK/6:2/2016 (H9N2) FOR PRODUCING INACTIVATED AND LIVE INFLUENZA VACCINES | 2018 |
|
RU2702833C1 |
| STRAIN OF INFLUENZA VIRUS A/UNL/HK/2:6/2017 (H5N8) FOR PRODUCING INACTIVATED AND LIVE INFLUENZA VACCINES | 2018 |
|
RU2702834C1 |
| A/SHANGHAI/HK/6:2/2013 (H7N9) INFLUENZA VIRUS STRAIN FOR THE PRODUCTION OF INACTIVATED AND LIVING INFLUENZA VACCINES | 2017 |
|
RU2664460C1 |
| REASSORTANT ReM8-VACCINE STRAIN OF SUPTYPE H1N1 INFLUENZA A VIRUS | 2011 |
|
RU2457245C1 |
| REASSORTANT INFLUENZA VIRUS STRAIN RN9/13-HUMAN A(H6N9) FOR NEURAMINIDASE ANTIBODY ASSAY IN INFLUENZA INFECTION AND VACCINATION | 2014 |
|
RU2587629C1 |
| RECOMBINANT STRAIN OF A/PR8-NS124-Luc INFLUENZA VIRUS AND METHOD FOR EVALUATING POST-VACCINAL NEUTRALIZING ANTIBODIES USING BIOLUMINESCENT DETECTION | 2019 |
|
RU2759054C2 |
| REASSORTANT RN A9-SWINE A(H7N1) INFLUENZA VIRUS STRAIN FOR NEURAMINIDASE ANTIBODY ASSAY IN INFLUENZA INFECTION AND VACCINATION | 2010 |
|
RU2428476C1 |
| INFLUENZA VIRUS STRAIN FOR PRODUCING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN | 2011 |
|
RU2464311C1 |
