FIELD: medicine.
SUBSTANCE: method involves the introduction of lead acetate with underlying experimental hypercalcemia. Hypercalcemia is created by using the preparation Aquadetrim introduced in animals once a day daily through a probe into a stomach in dose 3000 IU/100 g for 30 days. In 14 days from the beginning of the experiment, it is combined with the subcutaneous introduction of lead acetate 40 mg/kg at a metal basis for 16 days.
EFFECT: reduced toxic action, including on kidneys with the controlled blood calcium content and the required toxic lead dose in experiment.
2 dwg, 5 tbl, 1 ex
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Authors
Dates
2012-08-10—Published
2010-12-03—Filed