METHOD FOR RELIEVING LEAD ACETATE NEPHROTOXICITY Russian patent published in 2012 - IPC G09B23/28 A61K31/593 A61P13/12 

Abstract RU 2458410 C1

FIELD: medicine.

SUBSTANCE: method involves the introduction of lead acetate with underlying experimental hypercalcemia. Hypercalcemia is created by using the preparation Aquadetrim introduced in animals once a day daily through a probe into a stomach in dose 3000 IU/100 g for 30 days. In 14 days from the beginning of the experiment, it is combined with the subcutaneous introduction of lead acetate 40 mg/kg at a metal basis for 16 days.

EFFECT: reduced toxic action, including on kidneys with the controlled blood calcium content and the required toxic lead dose in experiment.

2 dwg, 5 tbl, 1 ex

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RU 2 458 410 C1

Authors

Akhpolova Varvara Olegovna

Brin Vadim Borisovich

Zaks Tamaz Vladislavovich

Dates

2012-08-10Published

2010-12-03Filed