METHOD FOR PREVENTION OF TOXIC ACTION OF CADMIUM IN EXPERIMENTAL ANIMALS SUFFERING CHRONIC POISONING Russian patent published in 2012 - IPC G09B23/28 A61K31/593 A61K33/06 A61P13/12 

Abstract RU 2462763 C1

FIELD: medicine.

SUBSTANCE: toxic action of cadmium is experimentally simulated by the daily subcutaneous introduction of a cadmium sulphate solution 0.3 mg/kg on a metal basis wherein a unit of the solution 1 ml is equal to cadmium 0.3 mg. A preventive agent is presented by Aquadetrim 25000 IU/kg and 10% calcium chloride 1.5 ml/ kg of body weight. Said preparations are introduced simultaneously daily through a probe in a stomach once a day for 30 days. For the following 30 days, said preparations are introduced daily 1 hour before the subcutaneous injection of cadmium sulphate.

EFFECT: effective reduction of toxic action of cadmium on the body, particularly nephropathic action ensured by changed calcium hemostasis.

2 dwg, 5 tbl, 1 ex

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RU 2 462 763 C1

Authors

Khadartseva Madina Petrovna

Brin Vadim Borisovich

Zaks Tamaz Vladislavovich

Dates

2012-09-27Published

2011-07-13Filed