FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, namely protective compositions for ischemia/reperfusion containing at least one ketone body specified in β-hydroxybutyrate, acetoacetate and their pharmaceutically acceptable salts and melatonin.
EFFECT: invention represents methods for using such compositions for reducing or preventing an ischemic/reperfusion disorder caused by blood loss, apoplexy or cardiopulmonary shock, or surgical intervention.
43 cl, 6 ex, 4 tbl, 32 dwg
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