PHARMACEUTICAL COMBINATIONS OF ANGIOTENSINE RECEPTOR ANTAGONIST AND NEP INHIBITOR Russian patent published in 2012 - IPC C07D257/04 A61K31/216 

Abstract RU 2459809 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is described is a specific combination - [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3'-methyl-2'-(valeroyl{2"-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate] trisodium salt pentahydrate in a solid state which is a double-action compound of angiotensin receptor antagonist and NEP inhibitor, a method for preparing it, a pharmaceutical composition and using said combination for hypertension and cardiac failure.

EFFECT: preparing the combination for hypertension and cardiac failure.

16 cl, 5 ex, 1 tbl

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RU 2 459 809 C2

Authors

Fehn Lili

Godtfredsen Sven Ehrik

Karpinski P'Otr

Satton Pol Allen

Prashad Makhavir

Girgis Majkl Dzh.

Sjuj Bin'

Lju Jugan

Blehklok Tomas Dzh.

Dates

2012-08-27Published

2006-11-08Filed