FIELD: medicine, pharmaceutics.
SUBSTANCE: what is described is a specific combination - [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3'-methyl-2'-(valeroyl{2"-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate] trisodium salt pentahydrate in a solid state which is a double-action compound of angiotensin receptor antagonist and NEP inhibitor, a method for preparing it, a pharmaceutical composition and using said combination for hypertension and cardiac failure.
EFFECT: preparing the combination for hypertension and cardiac failure.
16 cl, 5 ex, 1 tbl
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Authors
Dates
2012-08-27—Published
2006-11-08—Filed