NEP INHIBITORS FOR TREATMENT OF DISEASES CHARACTERIZED BY ATRIAL ENLARGEMENT OR REMODELING Russian patent published in 2023 - IPC A61K31/195 A61P9/00 A61P9/06 

Abstract RU 2809222 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to the treatment of heart failure with preserved ejection fraction. The following is disclosed: the use of trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-(S)-3'-methyl-2'-(pentanoyl{2''-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate]hemipentahydrate (LCZ696) to improve, stabilize, or slow the worsening of the NYHA classification in patients with heart failure with preserved ejection fraction (HFpEF).

EFFECT: use of the invention makes it possible to effectively improve, stabilize and/or slow down the deterioration of the condition of patients suffering from heart failure with preserved ejection fraction.

10 cl, 1 dwg, 2 tbl, 9 ex

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RU 2 809 222 C2

Authors

Shumakher Kristof

Kholbro Tomas

Dates

2023-12-07Published

2018-07-20Filed