DIAGNOSTIC TECHNIQUE FOR TOXIC ENCEPHALOPATHY IN SMALL LABORATORY ANIMALS IN CHRONIC ACTION OF METALLIC MERCURY VAPOUR Russian patent published in 2012 - IPC G09B23/28 A61B5/476 

Abstract RU 2461893 C2

FIELD: medicine.

SUBSTANCE: electroencephalography is performed; β2 - and δ - rhymes are recorded in F4 and P3 lead; a canonical variate is calculated by formula: Cv=1.6+1.6xa1-1.2xa2+0.7xa3-0.4xa4-) wherein Cv is the canonical value 1.6; -1.2; 0.7; -0.4 are discriminant coefficients; 1,6 is a constant; a1,2,3,4 are numerical values of research results of bioelectric cerebral activity: a1 is a percentage β2 of P3-lead rhythm, a2 is a percentage δ of P3-lead rhythm, a3 is a percentage δ of F4-lead rhythm, a4 is a percentage β2 of F4-lead rhythm. If the Cv value is more than 1.6, the absence of chronic action of mercury on the brain is stated; if the Cv is 1.6 or less, toxic encephalopathy is diagnosed in the animal.

EFFECT: method extends the range of the agents for diagnosing of toxic encephalopathy in small laboratory animals in chronic action of metallic mercury vapour.

1 tbl, 3 ex

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RU 2 461 893 C2

Authors

Katamanova Elena Vladimirovna

Sosedova Larisa Mikhajlovna

Jakimova Natal'Ja Leonidovna

Konstantinova Tat'Jana Nikolaevna

Dates

2012-09-20Published

2010-11-15Filed