METHOD FOR EVALUATING DEGREE OF MANIFESTATION OF METAL MERCURY VAPOUR INTOXICATION Russian patent published in 2015 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: blood serum is measured for interleukine 2, S-100 protein autoantibodies, β₂-glycoprotein antibodies, MAG autoantibodies specific to the nerve tissue. The diagnostic coefficients F₁ and F₂ are calculated: F₁=-14.12+20.89×A₁+34.74×A₂-0.004×A₃+0.0004×A₄; F₂=-9.85+4.89×A₁+10.08×A₂+0.006×A₃+0.011×A₄, wherein -14.12 and -9.85 are constants 20.89; 34.74; 0.011; 0.0004; 4.89; 10.08; 0.006; 0.004 are discriminator coefficients; A₁, …₄ are gradations and numerical values of the examination: A₁ is measured interleukin 2, pg/ml; A₂ is measured S-100 protein autoantibodies, standard units; A₃ is measured β₂-glycoprotein antibodies, standard units; A₄ is MAG, BTU autoantibodies. If F₁ is found to exceed F₂, organic changes specific for degree 2 chronic mercury intoxication are diagnosed; if F₁ is less than or equal to F₂, the initial manifestations of metal mercury vapour intoxication are stated that testifies to degree 1 intoxication.

EFFECT: using this method enables differentiating the degree of manifestation of chronic mercury intoxication by using a complex of immunological values, including the antibodies specific to the nerve tissue in the chronic exposure to metal mercury vapours.

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