METHOD OF ESTIMATING INTENSITY OF DESTRUCTIVE PROCESSES IN CASE OF KNEE JOINT TRAUMATIC INJURY AND PREDICTION OF DEVELOPMENT OF POST-TRAUMATIC ARTHROSIS Russian patent published in 2012 - IPC A61B10/00 G09B23/28 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to traumatology and orthopedics. In order to estimate intensity of destructive processes in case of knee joint traumatic injury and prediction of development of post-traumatic arthrosis, content of oxyprolene in determined in rats after modelling of knee joint trauma. Content of protein-bounded oxyprolene in plasma higher than 75 mcmol/l with simultaneous increase of free fraction of oxyprolene higher than 16 mcmol/l testified to active reparation at the background of continuing intensive destruction of collagen structures resulting in deforming osteoarthrosis.

EFFECT: method increases accuracy of estimation of destructive processes intensity in case of traumatic injury of knee joint and prediction of development of post-traumatic arthrosis due to determination of quantitative and fractional content of oxyprolene.