METHOD FOR ASSESSING FUNCTIONAL RESERVES OF HUMAN BODY Russian patent published in 2012 - IPC G01N33/48 G01N33/497 

FIELD: medicine.

SUBSTANCE: what is conducted is 10-minute hypoxic loading test (LT) using oxygen poor (up to 10-11%) normobaric gas mixture with reoxygenation time recorded and physiological parameters controlled. It is followed by calculating a functional deviation coefficient (C_f) in standard units by formula: C_f=ΔRR/10+ΔHR/10+ΔSBP/10+ΔDBP/10+ΔSaO₂/10+T_r/60, wherein ΔRR/10 is a gradient of respiratory rate (respiratory rate increment for a hypoxic time divided by 10), standard units; ΔHR/10 is a gradient of heart rate (heart rate increment for a hypoxic time divided by 10), standard units; ΔSBP/10 is a gradient of systolic blood pressure (increase/decrease of systolic blood pressure (mm Hg) for a hypoxic time divided by 10), standard units; ΔDBD/10 is a gradient of diastolic blood pressure (increase/decrease of diastolic blood pressure (mm Hg) for a hypoxic time divided by 10), standard units; ΔSaO₂/60 is a gradient of SaO₂ (decrease of arterial oxygen saturation (%) for a hypoxic time divided by 10), standard units; T_r/60 is a gradient of reoxygenation (a reoxygenation time (sec.) divided by 60), standard units. If C_f≤6.5, an optimum level of functional reserves is stated; the value 6.5<C_f≤12 means decrease of functional reserves; while depleted functional reserves are shown by the value C_f>12.

EFFECT: use of the method enables the objective assessment of manifestation of the deviations, including the pre-clinical one for the purpose of directed correction.

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