METHOD FOR PREPARING HIGH-PURITY Ga SOLUTIONS Russian patent published in 2012 - IPC A61K51/00 A61K103/00 B01D15/42 G01N30/02 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to methods for preparing ⁶⁸Ga solutions which involves the following stages: reaction of ⁶⁸Ge/⁶⁸Ga generator eluate and cation-exchange resin, washing of cation-exchange resin in the mixture of 0.2-1 M hydrochloric acid and 20-80 vol. % of acetone, eluation of ⁶⁸Ga with cation-exchange resin by the mixture of 1.8-2.5 M hydrochloric acid and 20-80 vol. % of acetone, reaction of the prepared eluate and anion-exchange resin, washing of anion-exchange resin in an organic solvent, drying of anion-exchange resin by air and neutral gas and eluation of ⁶⁸Ga with anion-exchange resin by an aqueous solution of 0.01-0.1 M hydrochloric acid wherein it's amount is 15-25 less than that of the initial ⁶⁸Ge/⁶⁸Ga generator eluate. EFFECT: method provides preparing the concentrated solutions of the ⁶⁸Ga radionuclides of high chemical and radiochemical purity containing no organic solvents that enables preparing the ⁶⁸Ga radiopharmaceutical of high molar activity and radiochemical purity.

2 cl, 3 tbl, 2 dwg, 4 ex