FIELD: medicine.
SUBSTANCE: diagnostic RN2/57-human A(H7N2) influenza virus strain is produced by cross breeding of the sterile equine influenza virus A/horse/Prague/1/1956(H7N7) and the cold-adapted vaccine strain A/17/duck/Potsdam/86/92(H5N2) on the basis of the attenuation donor A/Leningrad/134/17/5 7(H2N2). The strain contains neuraminidase of the subtype 2 influenza virus A/Leningrad/134/17/1957(H2N2) and hemagglutinin of equine influenza virus A/horse/Prague/1/1956(H7N2). The RN2/57-human A(H7N2) strain replicates actively in growing chicken embryos at optimum temperature 33°C that enables collecting the viral material to be purified and concentrated.
EFFECT: invention may be used for detection neuraminidase antibodies of the N2 influenza virus in serums of experimental animals and volunteers with the use of solid-phase sialydase activity neuraminidase inhibition test.
1 dwg, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| REASSORTANT RN A9-SWINE A(H7N1) INFLUENZA VIRUS STRAIN FOR NEURAMINIDASE ANTIBODY ASSAY IN INFLUENZA INFECTION AND VACCINATION | 2010 |
|
RU2428476C1 |
| REASSORTANT STRAIN OF RN2/66-HUMAN A (H7N2) INFLUENZA VIRUS FOR NEURAMINIDASE ANTIBODIES IDENTIFICATION IN CASE OF INFLUENZA INFECTION AND VACCINATION | 2016 |
|
RU2625024C1 |
| REASSORTANT INFLUENZA VIRUS STRAIN RN9/13-HUMAN A(H6N9) FOR NEURAMINIDASE ANTIBODY ASSAY IN INFLUENZA INFECTION AND VACCINATION | 2014 |
|
RU2587629C1 |
| STRAIN OF INFLUENZA VIRUS GKV 2389 FOR PRODUCTION OF LIVING INTRANASAL AND INACTIVATED INFLUENZA VACCINE | 2006 |
|
RU2318871C1 |
| REASSORTANT STRAIN OF INFLUENZA VIRUS RN2/14-HUMAN A(H6N2) FOR DETECTING NEURAMINIDASE ANTIBODIES IN INFLUENZA INFECTION AND VACCINATION | 2019 |
|
RU2716416C1 |
| INFLUENZA VIRUS STRAIN FOR PRODUCING LIVE AND INACTIVATED INFLUENZA VACCINE | 2011 |
|
RU2464309C1 |
| STRAIN OF INFLUENZA VIRUS A/17/MALLARD/NETHERLANDS/00/95(H7N3) FOR PRODUCTION OF LIVE AND INACTIVATED INFLUENZA VACCINES | 2012 |
|
RU2507256C2 |
| INFLUENZA VIRUS STRAIN A/17/Anui/2013/61 (H7N9) FOR PRODUCTION OF LIVE INTRANASAL INFLUENZA VACCINE | 2013 |
|
RU2563351C2 |
| REASSORTANT INFLUENZA VIRUS STRAIN A/17/SILVER GULL/SARMA/06/887 (H6N1) FOR PREPARING LIVE INFLUENZA VACCINE | 2015 |
|
RU2606026C1 |
| STRAIN OF INFLUENZA VIRUS A (H1N1) FOR PREPARING OF LIVING INFLUENZA INTRANASAL VACCINE FOR ADULT AND CHILDREN | 1991 |
|
RU2031941C1 |
