FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology. Invention represents RN2/14-human A(H6N2) strain actively propagating in developing chick embryos at the optimum temperature of 33 °C, which enables to accumulate viral material for further purification and concentration. Reassortant inherited a gene which codes the surface antigen of the haemagglutinin virus (HA) and six genes coding internal and non-structural proteins from A/17/silver gull/Sarma/06/887 (H6N1), and the gene coding the surface antigen of the virus neuraminidase (NA), from A/17/Hong Kong/2014/8296 (H3N2).
EFFECT: strain RN2/14-human A(H6N2) can be used for detecting antibodies to neuraminidase N2 of influenza virus in blood serum using solid-phase inhibition reaction of neuraminidase activity.
1 cl, 4 dwg
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Authors
Dates
2020-03-11—Published
2019-09-24—Filed