METHOD FOR EARLY PREDICTION OF CLINICAL EFFECTIVENESS IN PATIENTS WITH NEWLY DIAGNOSED INFILTRATIVE PULMONARY TUBERCULOSIS Russian patent published in 2012 - IPC G01N33/92 

FIELD: medicine.

SUBSTANCE: there are involved laboratory studies, namely calculating a prognostic index of three-month clinical effectiveness with regard to bacterioexcretion massivity. If observing no or poor bacterioexcretion (0-20 colony-forming units) enables calculating the prognostic index by formula: Y= -0.687×X₁ - 6.772×X₂ + 0.058×X₃+32.5. Moderate or massive bacterioexcretion (>20 colony-forming units) provides calculating the prognostic index by formula: Y= -73.5×X₄ - 4.89×X₂ - 0.05×X₃ + 48.94. The values Y>0 enables to predict the disappear of intoxication symptoms and cavity closure, while Y<0 shows the cavity decrease and disappear of intoxication symptoms.

EFFECT: use of the declared method enables high-reliability early prediction of three-month clinical effectiveness in the patients suffering infiltrative destructive pulmonary tuberculosis on the basis of the study of a minimum number of the biochemical values and bacterioexcretion massivity for the purpose of early optimisation of the anti-tuberculosis therapy.

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