LOCAL APPLICATION AND ERYTHROPOIETIN PREPARATIONS FOR SKIN WOUND HEALING Russian patent published in 2012 - IPC A61K38/18 A61K9/10 A61K47/38 A61P17/02 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and pharmaceutical application and represents a gel or viscous composition applicable for local wound healing on injured skin, containing erythropoein (EPO) and at least one swelling gel-forming polysaccharide in the concentration of 0.4-4 wt %/wt specified from one or more than one member of the group consisting of: hydroxyethyl cellulose, hydroxymethyl cellulose, carboxyethyl cellulose, carboxymethyl cellulose which can be prepared by mixing EPO in a lyophilised or suspended form with the pre-swelled polysaccharide of viscosity less than 5000 mPa*s, and initiating complete swelling wherein completely swelled polysaccharide has viscosity 20000-60000 mPa*s, and EPO is found in the concentration of 100-500 IU/g of the gel composition wherein said mixing is ensured by EPO diffusion in a gel for at least 24 h.

EFFECT: invention provides stabilisation of the active compound and its uniform release, as well as effective therapy of injuries or pathologically induced skin injury.

13 cl, 17 ex, 6 dwg