NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, SYNTHESIS AND USE THEREOF AS ANTIBACTERIAL MEDICINAL AGENTS Russian patent published in 2012 - IPC C07D471/18 C07D471/08 A61K31/529 A61P31/00 

Abstract RU 2465276 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula (I), having antibacterial properties, a method for synthesis thereof, use thereof and a pharmaceutical composition based on said compounds. In general formula (I) R1 is a (CH2)n-NH2 or (CH2)n-NHR radical, where R is (C1-C6)alkyl and n equals 1 or 2; R2 is a hydrogen atom; R3 and R4 together form a nitrogen-containing aromatic 5-member heterocycle with 1, 2 or 3 nitrogen atoms, possibly substituted with one or more R' groups, where R' is selected from a group consisting of a hydrogen atom and alkyl radicals with 1-6 carbon atoms.

EFFECT: improved method.

13 cl, 4 ex

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RU 2 465 276 C2

Authors

Lampila Maksim

Rouland David Alehn

Kebsi Adel'

Ledussal' Benua

P'Er Kamil'

Dates

2012-10-27Published

2008-04-11Filed