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(19)

(11)

2 572 593

(13)

(51)

IPC

C07D403/12(2006-01-01)

C07D403/14(2006-01-01)

C07D405/14(2006-01-01)

C07D409/14(2006-01-01)

C07D413/14(2006-01-01)

C07D471/04(2006-01-01)

C07D471/08(2006-01-01)

C07D487/04(2006-01-01)

C07D487/08(2006-01-01)

C07D401/14(2006-01-01)

A61K31/4155(2006-01-01)

A61K31/439(2006-01-01)

A61K31/497(2006-01-01)

A61K31/4985(2006-01-01)

A61K31/496(2006-01-01)

A61K31/454(2006-01-01)

A61K31/501(2006-01-01)

A61K31/5377(2006-01-01)

A61P7/02(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2013151293/04, 2011-09-13

(24)

Start date

2011-09-13

(22)

Actual filing date

2011-09-13

(45)

Published

2016-01-20

(72)

Inventor

Badork AlanBoldron KristofDelesk NataliFossi ValeriLassall' Zhil'BerIvon Ksav'E

(73)

Holder

Sanofi

N-[(1H-PYRAZOL-1-YL) ARYL]-1H-INDOLE OR 1H-INDAZOLE-3-CARBOXAMIDE DERIVATIVES, PRODUCING AND USING THEM AS P2Y12 ANTAGONISTS Russian patent published in 2016 - IPC C07D403/12 C07D403/14 C07D405/14 C07D409/14 C07D413/14 C07D471/04 C07D471/08 C07D487/04 C07D487/08 C07D401/14 A61K31/4155 A61K31/439 A61K31/497 A61K31/4985 A61K31/496 A61K31/454 A61K31/501 A61K31/5377 A61P7/02 A61P9/10

Abstract RU 2572593 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to compounds characterised by general formula (I), wherein A represents an aromatic diradical specified in groups having formulas such as below whereas the other radical and groups have values presented in the patent claim.

EFFECT: invention refers to methods for producing the compounds of formula (I) , pharmaceutical composition containing them, and using them as P2Y12 antagonists for treating cardiovascular diseases.

14 cl, 16 tbl, 21 ex

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RU 2 572 593 C2

Authors

Badork Alan

Boldron Kristof

Delesk Natali

Fossi Valeri

Lassall' Zhil'Ber

Ivon Ksav'E

Dates

2016-01-20—Published

2011-09-13—Filed