PROGESTERONE ANTAGONISTS Russian patent published in 2017 - IPC C07J1/00 C07J21/00 C07J41/00 C07J43/00 C07J51/00 C07J71/00 A61K31/58 A61K31/567 A61P5/36

Abstract RU 2608521 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to compounds of formula (I) possessing antiprogestin properties, and to a method for treating breast cancer using such compounds. In general formula (I) X is O; R¹, R², R³ and R⁴ is hydrogen atoms; R⁵ is a radical Y, Y is acetyl, C₃-cycloalkyl or pyridinyl; R⁶ is -OH; and R⁷ is a radical of formula C_nF_mH_o, where n is 3, m is 2 or 3, o is 2 or 3 and m plus o is equal to 5.

EFFECT: disclosed is a compound of formula (I) possessing antiprogestin properties.

5 cl, 1 tbl, 4 ex

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RU 2 608 521 C2

Authors

Nickisch Klaus

Narkunan Kesavaram

Debnath Baishakhi

Santhamma Bindu

Dates

2017-01-19—Published

2012-07-30—Filed