FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, namely to ophthalmology and can be used for treatment of glaucoma or higher intraocular pressure (IOP) in patient. For this purpose efficient amount of composition, containing preparation inhibiting PAI-1 binding with vitronectin, is introduced to patient. Also claimed is method of treating PAI-1-associated eye disease.
EFFECT: group of inventions ensures treatment of glaucoma and IOP due to reduction of separation of trabecular meshwork tissue and reduction of increased resistance to intraocular fluid outflow, and also due to increase of TM tissue cellularity and preservation of phagocytosis.
14 cl, 8 dwg, 8 ex
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Authors
Dates
2012-11-10—Published
2007-10-31—Filed