FIELD: medicine.
SUBSTANCE: invention refers to medicine, and concerns mediated PHKi inhibition of RHO-kinase for treating ophthalmic disorders. The substance of the invention involves RNA-interference for mRNA Rho-kinase expression inhibition for treating patients with ophthalmic disorders, especially for treating intraocular pressure, eye hypertension and glaucoma The mRNA Rho-kinase targets include gene ROCK 1 mRNA.
EFFECT: creation of the agent exhibiting improved properties.
56 cl, 2 ex, 4 dwg, 1 tbl
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Authors
Dates
2011-10-27—Published
2006-12-19—Filed