FIELD: chemistry.
SUBSTANCE: present invention relates to a method of producing 17α-(3-hydroxypropyl)-17β-hydroxysteroids of formula I
,
from 17-ketosteroids of formula III
through intermediate compounds of formula V
,
where radicals R3, R5, R6, R7, R10, R13, R15, R16, R40, R41 and R42 have values given in the description.
EFFECT: high efficiency of the method.
13 cl, 3 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 18-METHYL-19-NORANDROST-4-ENE-17,17-SPIROETHER (18-METHYL-19-NOR-20-SPIROX-4-EN-3-ON) AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUND | 2007 |
|
RU2440365C2 |
| 17 β -OXYESTRATRIENES | 2002 |
|
RU2339643C2 |
| UNSATURATED 14,15-CYCLOPROPANOANDROSTANES, METHOD FOR THEIR PREPARING, COMPOUNDS, PHARMACEUTICAL COMPOSITION | 2000 |
|
RU2244718C2 |
| 16α-BROMO-3β-HYDROXY-5α-ANDROSTANE-17-ONE SEMIHYDRATE, METHOD FOR ITS PREPARING, PHARMACEUTICAL COMPOSITIONS, USING COMPOUNDS | 2000 |
|
RU2295534C2 |
| COMPOUNDS, SET, ANDROGENIC COMPOSITION | 2000 |
|
RU2242479C2 |
| DROSPIRENONE FOR HORMONAL REPLACEMENT THERAPY | 2005 |
|
RU2402331C2 |
| HORMONAL OR ANTI-HORMONAL STEROID COMPOUNDS, METHODS FOR THERAPEUTIC EFFECT, METHOD FOR PREPARING COMPOUNDS | 1999 |
|
RU2238943C2 |
| DROSPYRENON FOR REPLACEMENT HORMONOTHERAPY | 2001 |
|
RU2275198C2 |
| 15,15-DIALKYLSTEROID COMPOUNDS AND METHOD OF PREPARATION THEREOF | 1994 |
|
RU2147306C1 |
| COMBINATIONS OF ACTIVATOR (ACTIVATORS) OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR), AND INHIBITOR (INHIBITORS) OF STEROL ABSORPTION AND TREATMENT OF VASCULAR DISEASES | 2008 |
|
RU2483724C2 |
