COMPOUNDS, SET, ANDROGENIC COMPOSITION Russian patent published in 2004 - IPC

FIELD: organic chemistry, steroids, medicine, andrology.

SUBSTANCE: invention relates to steroids of the general formula (I):

wherein R₁ means oxygen atom (O), (H,H), (H,OR), NOR wherein R means hydrogen atom (H), (C₁-C₆)-alkyl, (C₁-C₆)-acyl; R₂ means hydrogen atom (H) or (C₁-C₆)-alkyl; R₃ means hydrogen atom (H); or R₃ means (C₁-C₆)-alkyl, (C₂-C₆)-alkenyl, (C₂-C₆)-alkynyl possibly substituted with halogen atom; R₄ means hydrogen atom (H), (C₁-C₆)-alkyl or (C₂-C₆)-alkenyl; R₅ means (C₁-C₆)-alkyl; R₆ means hydrogen atom (H); R₇ means hydrogen atom (H), (C₁-C₆)-alkyl; R₈ means hydrogen atom (H), hydroxyl (OH), halogen atom; R₉ and R₁₀ mean independently hydrogen atom (H); or R₉ and R₁₀ mean independently (C₁-C₆)-alkyl possibly substituted with (C₁-C₄)-alkoxy-group or halogen atom; R₁₁ means hydrogen atom (H), -SO₃H, (C₁-C₁₅)-acyl; dotted line means the possible bond among Δ⁴-, Δ⁵⁽¹⁰⁾- or Δ^4,9-diene system. Compounds elicit the general androgenic activity and can be used for preparing agent used for male contraception.

EFFECT: valuable medicinal properties of compounds and composition.

9 cl, 18 ex