FIELD: medicine.
SUBSTANCE: invention refers to a pharmaceutical composition for prevention and treatment of diabetes mellitus and obesity containing as active ingredients a compound inhibiting activity of dipeptidylpeptidase-IV (DPP-IV), its pharmaceutically acceptable salt, its hydrate or its solvate, and one or more other antidiabetic agents or antiobesity agents.
EFFECT: pharmaceutical composition shows excellent improvement of glucose tolerance and may be used in prevention and treatment of diabetes mellitus, obesity and similar diseases, effectively reducing blood glucose level and weight.
25 cl, 8 dwg, 17 tbl, 32 ex
Title |
Year |
Author |
Number |
DPP-IV INHIBITOR CONTAINING BETA AMINO GROUP, METHOD FOR MAKING THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING IT FOR PREVENTION AND TREATMENT OF DIABETES OR OBESITY |
2008 |
- Kim Kheung Dzae
- Kvak Voo Jang
- Shin Chang Jell
- Kim Khadong
- Min Dzong Pil
- Park Kiung Dzin
- Li Dzae Jang
- Choi Song-Khien
- Joon Tae Khiun
- Kim Khae-Sun
- Dzang Dzi Miun
- Kim Mi-Kiung
- Son Moon-Kho
- Kim Soon Khoe
- Joo Mookhi
|
RU2419615C1 |
DERIVATIVES OF HEXAHYDRODIAZEPINONE, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND USING IN PREPARING MEDICINAL AGENT FOR TREATMENT OF NON-INSULIN DEPENDENT DIABETES MELLITUS |
2003 |
- Biftu Tesfaje
- Ljang Guj-Baj
- Tsjan' Sjaosja
- Uehber Ehnn Eh.
- Fehn Dantsin Dennis
|
RU2301803C2 |
TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVE SALTS, METHODS FOR PREPARING THEM AND MEDICAL APPLICATION THEREOF |
2010 |
- Tan Pehn Cho
- Sun' Pjaojan
- Jan Fanlon
- Ljan Tszin'Dun
- Shehn' Guanjuan'
- Van Jan
- Fan' Tszjan
|
RU2523543C2 |
IMPROVED METHOD OF PRODUCING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE COMPOUND |
2010 |
- Kwak Woo Young
- Kim Heung Jae
- Min Jong Pil
- Yoon Tae Hyun
- Shim Hyun Joo
- Yoo Moohi
|
RU2498976C9 |
IMPROVED METHOD OF PRODUCING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE COMPOUND |
2010 |
- Kwak Woo Young
- Kim Heung Jae
- Min Jong Pil
- Yoon Tae Hyun
- Yoo Moohi
- Lim Geun Gho
- Chang Sun Ki
|
RU2499792C2 |
METHYL(R)-7-[3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)-BUTYRYL]-3-TRIFLUOROMETHYL-5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-a]PYRAZINE-1-CARBOXYLATE SALTS |
2010 |
- Juan' Kajkhun
- Ma Shutsin'
- Chzhu Lin'
- Lju Khuavehn'
|
RU2528233C2 |
COMBINATION CONTAINING NEW DERIVATIVE 3-(4-(BENZYLOXY)PHENYL)HEX-4-IN-ACID AND OTHER ACTIVE INGREDIENT TO ACTIVATE G-PROTEIN 40 OF THE RECEPTOR ENZYME |
2015 |
- Yan Dzhin
- Kim Dzhin Voon
- Li Khan Kyu
- Kim Dzhe Khyun
- Son Chan Mo
- Li Kyu Khvan
- Choj Khyun-Kho
- Kim Dekhoon
- Kha Te-Eun
- Rkhee Dzhekol
|
RU2680248C1 |
PHARMACEUTICAL COMPOSITION FOR TREATING TYPE 2 DIABETES |
2010 |
- Juan' Kajkhun
- Sun' Pjaojan
|
RU2533560C2 |
AMINOTETRAHYDROPYRANES AS DIPEPTIDYLPEPTIDASE-IV INHIBITORS FOR TREATING OR PREVENTING DIABETES |
2010 |
- Biftu Tesfaje
- Chehn' Pin
- Fehn Dan'Tsin
- Tsjan' Sjaosja
|
RU2550508C2 |
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF DIABETES AND RELATED METABOLIC DISEASES |
2021 |
- Kim, Mi-Kiung
- Kim, Tae Khioung
- Dzung, Ii Khoon
- Chae, Yu Na
- Yang, Dzae Sung
|
RU2809286C1 |