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2 468 000

(13)

(51)

IPC

C07C229/46(2006-01-01)

A61K31/195(2006-01-01)

A61P25/18(2006-01-01)

(21) (22)

Application

2011108063/04, 2011-03-03

(24)

Start date

2011-03-03

(22)

Actual filing date

2011-03-03

(45)

Published

2012-11-27

(72)

Inventor

Jashin Nikolaj VladimirovichChemagin Andrej Valer'EvichKuznetsova Tamara StepanovnaZefirov Nikolaj Serafimovich

(73)

Holder

Zapol'Skij Maksim Ehduardovich

SPIROCYCLIC CYCLOPROPANE AMINO ACIDS - ANALOGUES OF GAMMA-AMINOBUTYRIC ACID, WITH LIMITED CONFORMATIONAL MOBILITY AND BASED ON THEM PHARMACEUTICAL COMPOSITIONS Russian patent published in 2012 - IPC C07C229/46 A61K31/195 A61P25/18

Abstract RU 2468000 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel spirocyclic cyclopropane amino acids of general formula I, demonstrating antipsychotic, antidepressant, anticonvulsant and anxiolytic properties. In formula I n = 0-3, Z = CR⁶R⁷, R¹-R⁷ represent hydrogen.

EFFECT: invention also relates to pharmaceutical composition, containing said amino acids of general formula I.

3 cl, 1 tbl, 3 ex

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RU 2 468 000 C2

Authors

Jashin Nikolaj Vladimirovich

Chemagin Andrej Valer'Evich

Kuznetsova Tamara Stepanovna

Zefirov Nikolaj Serafimovich

Dates

2012-11-27—Published

2011-03-03—Filed