FIELD: chemistry.
SUBSTANCE: invention relates to field of biologically active compounds and relates to novel dipeptides of formula R1-C(O)-X-Trp-Y-Ile-R2, where X = L or D configuration, Y = L configuration; R1 = C6H5-CH2-O, or C6H5-(CH2)5, or C6H5-CH2; R2 = OH, or NH2, or NHCH3, possessing neuropsychotropic activity, in particular anxiolytic.
EFFECT: obtaining novel biologically active compounds.
9 cl, 10 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| TSPO DIPEPTIDE LIGANDS HAVING NEUROPSYCHOTROPIC ACTIVITY | 2018 |
|
RU2756772C2 |
| TRIPEPTIDE HAVING NEUROPSYCHOTROPIC ACTIVITY | 2023 |
|
RU2823022C1 |
| LEUCYLTRYPTOPHAN TSPO LIGANDS WITH ANXIOLYTIC ACTIVITY | 2020 |
|
RU2757476C2 |
| NOVEL GLYPROLINS WITH NOOTROPIC, ANTI-HYPOXIC, NEUROPROTECTIVE AND ANSSIYLITIS ACTIVITY | 2016 |
|
RU2646604C2 |
| AGENTS ENHANCING GROWTH HORMONE SECRETION | 2001 |
|
RU2270198C2 |
| DIPHENYLPYRROLO[1,2-A]PYRAZINE-3-CARBOXAMIDES-COMPOUNDS HAVING NEUROPSYCHOTROPIC ACTIVITY, METHODS FOR PREPARING THEM | 2018 |
|
RU2734240C2 |
| PYRROLO[1,2-A]PYRAZINE-CONTAINING LIGANDS OF THE 18 KDA TRANSLOCATOR PROTEIN WITH ANXIOLYTIC ACTIVITY | 2022 |
|
RU2812083C2 |
| DERIVATIVES OF N-ACYLPROLYLDIPEPTIDES | 1993 |
|
RU2119496C1 |
| AMIDES OF 3-SUBSTITUTED 5- AND 6-AMINOALKYLINDOLE-2-CARBOXYLIC ACID AND RELATED ANALOGUES SUCH AS CASEIN KINASE IΕ INHIBITORS | 2005 |
|
RU2369599C2 |
| 1-ARYLPYRROLO[1,2A]PYRAZINE-3-CARBOXAMIDES WITH NEUROPSYCHOTROPIC ACTIVITY | 2014 |
|
RU2572076C2 |
