FIELD: medicine.
SUBSTANCE: after operation a section of tumour is taken from patient, placed into diffusion chamber together with solution of chemical preparation, chamber is placed into peritoneal cavity of rat for 1 week. After that animals are removed from experiment, fixation, staining and light microscopy of filter from chamber are performed, sensitivity of tumour to said chemical preparation is determined by presence or absence of tumour cell growth. After that, since the eighth day after operation patient is subjected to intraperitoneal autoplasmachemical therapy for 5 days with the preparation to which tumour is sensitive.
EFFECT: increase of anti-tumour action of intraperitoneally introduced cytostatics, incubated on autoplasma, due to individual selection of chemical preparation.
2 ex
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Authors
Dates
2011-02-27—Published
2009-07-16—Filed