METHOD OF ADJUVANT THERAPY OF COLORECTAL CANCER Russian patent published in 2013 - IPC A61K31/513 A61K31/519 A61M3/02 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely oncology, and may be used for an adjuvant therapy of colorectal cancer. That is ensured by the intraoperative insertion of a microirrigator into an abdominal cavity in a bed of the extracted tumour. On the 7th postoperative day, oxaliplatin 85 mg/m², and then leukovorin 200 mg/m² are administered intravenously drop-by-drop on the 1^st therapeutic day for 2 hours. Hyalobarrier gel 50 ml is put in a bottle with 5-fluorouracil 1000 mg/m², incubated for 30 minutes at 37°C, then the incubated gel is introduced into the abdominal cavity through the microirrigator from the bottle. On the 5^th therapeutic day, leukovorin 200 mg/m², then incubated Hyalobarrier gel with 5-fluorouracil are introduced in the patients intravenously drop-by-drop. Further, the microirrigator is removed from the abdominal cavity that is followed by a chemotherapy.

EFFECT: invention provides reducing a rate of remote metastases.

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