FIELD: chemistry.
SUBSTANCE: provided is a method of making ophthalmic devices such as contact lenses, involving steps of curing a reactive mixture containing at least one silicon-containing component, at least one hydrophilic component and at least one protonating diluent or protonated diluent having a Hansen solubility parameter, dp between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; and bringing the ophthalmic device into contact with an aqueous solution which is capable of altering the Hansen solubility parameter, dp of the protonating or protonated co-solvent in order to increase water-solubility and remove said diluent(s) from said aqueous solution.
EFFECT: silicone hydrogels are polymerised using a cheap and efficient method, which enables to obtain medical-quality articles.
25 cl, 1 dwg, 5 tbl, 28 ex
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