PROTEIN SHOWING INTERFERON-LIKE ANTIVIRAL AND ANTIPROLIFERATIVE BIOLOGICAL ACTIVITIES (VERSIONS), PROTEIN STRUCTURE, CODING POLYNUCLEOTIDE (VERSIONS), EXPRESSION VECTOR, HOST CELL, COMPOSITION AND USE OF PROTEIN AS ANTIVIRAL, ANTIPROLIFERATIVE, ANTICANCER OR IMMUNOMODULATORY AGENT AND METHOD OF TREATING CONDITION SENSITIVE TO INTERFERON-THERAPY, CANCER OR VIRAL DISEASE Russian patent published in 2012 - IPC C12N15/20 C07K14/555 C07K19/00 A61K38/21 A61P31/12 A61P35/00 A61P37/02

Abstract RU 2469091 C2

FIELD: medicine.

SUBSTANCE: what is produced is a recombinant protein created by gene shuffling possessing higher antiviral and antiproliferative activities as compared with existing human interferon-alpha-2b (HulFN-α2b). The prepared polypeptide is used in a composition as an antiviral, antiproliferative, anticancer or immunomodulatory agent.

EFFECT: invention enables using the prepared high-active interferon-like protein for treating a condition sensitive to interferon therapy, cancer or viral disease.

49 cl, 9 dwg, 8 tbl, 7 ex

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RU 2 469 091 C2

Authors

Van Khajtao

Mao Chunshen

Li Tszichzhi

Van Lin

Du Jun

Lju Lunbin'

Sjuj Tszin

Chzhan Zhuj

Dates

2012-12-10—Published

2007-06-22—Filed