METHOD OF PREDICTING HEMATOGENOUS METASTASES IN INTESTINAL TYPE OF STOMACH CANCER Russian patent published in 2012 - IPC G01N33/53 

Abstract RU 2470308 C1

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine and is intended for prediction of hematogenous metastases in intestinal type of stomach cancer. Immunohistochemical assessment of percent of expression of aldo-keto reductase family I member B10 (AKR1B10) protein in cells of intestinal type stomach cancer, forming glandular-like structures, located in mucous, submucous, muscular and serous layers of stomach wall, is performed. Regression coefficient β is calculated by method of multiple regression from software package Statistica 6,0 for Windows. If regression coefficient β value equals or is larger than "-0.25", case is referred to group of high risk of development of hematogenous metastases, if regression coefficient β value is less than "-0.25", case is referred to group of low risk of development of hematogenous metastases.

EFFECT: method makes it possible to increase accuracy of predicting risk of hematogenous metastases in case of intestinal type of stomach cancer.

2 ex, 5 dwg, 2 tbl

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RU 2 470 308 C1

Authors

Zav'Jalova Marina Viktorovna

Perel'Muter Vladimir Mikhajlovich

Stepanov Ivan Vadimovich

Vtorushin Sergej Vladimirovich

Cherdyntseva Nadezhda Viktorovna

Litvjakov Nikolaj Vasil'Evich

Afanas'Ev Sergej Gennad'Evich

Avgustinovich Aleksandra Vladimirovna

Savenkova Ol'Ga Vladimirovna

Grigor'Eva Evgenija Sergeevna

Beresten' Sergej Fedorovich

Volkomorov Viktor Vladimirovich

Dates

2012-12-20Published

2011-08-17Filed