FIELD: medicine.
SUBSTANCE: invention relates to field of medicine and is intended for prediction of hematogenous metastases in intestinal type of stomach cancer. Immunohistochemical assessment of percent of expression of aldo-keto reductase family I member B10 (AKR1B10) protein in cells of intestinal type stomach cancer, forming glandular-like structures, located in mucous, submucous, muscular and serous layers of stomach wall, is performed. Regression coefficient β is calculated by method of multiple regression from software package Statistica 6,0 for Windows. If regression coefficient β value equals or is larger than "-0.25", case is referred to group of high risk of development of hematogenous metastases, if regression coefficient β value is less than "-0.25", case is referred to group of low risk of development of hematogenous metastases.
EFFECT: method makes it possible to increase accuracy of predicting risk of hematogenous metastases in case of intestinal type of stomach cancer.
2 ex, 5 dwg, 2 tbl
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Authors
Dates
2012-12-20—Published
2011-08-17—Filed