METHOD FOR PREDICTION OF HAEMATOGENOUS METASTASIS IN TRIPLE NEGATIVE INVASIVE NON-SPECIFIC BREAST CARCINOMA Russian patent published in 2015 - IPC G01N33/574 

Abstract RU 2558863 C1

FIELD: medicine.

SUBSTANCE: method for prediction is implemented as follows: molecular-genetic type of breast cancer is determined by means of immune histochemical test of primary tumour tissue specimens taking into account the primary tumour size; the presence of lymphogenous metastases is detected; a structure of the primary tumour is morphologically studied by counting the number of different structure types in the infiltrative component of the tumour, and an intensity of tumour stroma hyalinosis is assessed. A probability of the haematogenous metastases is determined by formula. If P ≥ 50%, the high risk of the haematogenous metastases is stated. The value P < 50% shows the low risk.

EFFECT: method enables predicting the probability of the haematogenous metastases at higher accuracy and information value in triple negative invasive non-specific breast carcinoma and optimising the therapeutic approach to these patients.

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RU 2 558 863 C1

Authors

Zav'Jalova Marina Viktorovna

Slonimskaja Elena Mikhajlovna

Perel'Muter Vladimir Mikhajlovich

Vtorushin Sergej Vladimirovich

Telegina Nadezhda Semenovna

Bragina Ol'Ga Dmitrievna

Krakhmal' Nadezhda Valer'Evna

Dates

2015-08-10Published

2014-03-28Filed