FIELD: medicine.
SUBSTANCE: method for prediction is implemented as follows: molecular-genetic type of breast cancer is determined by means of immune histochemical test of primary tumour tissue specimens taking into account the primary tumour size; the presence of lymphogenous metastases is detected; a structure of the primary tumour is morphologically studied by counting the number of different structure types in the infiltrative component of the tumour, and an intensity of tumour stroma hyalinosis is assessed. A probability of the haematogenous metastases is determined by formula. If P ≥ 50%, the high risk of the haematogenous metastases is stated. The value P < 50% shows the low risk.
EFFECT: method enables predicting the probability of the haematogenous metastases at higher accuracy and information value in triple negative invasive non-specific breast carcinoma and optimising the therapeutic approach to these patients.
2 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF LYMPHATIC CANCER SPREAD ACCOMPANIED BY INVASIVE NONSPECIFIC TRIPLE-NEGATIVE BREAST CANCER | 2014 |
|
RU2558860C1 |
METHOD FOR PREDICTING LYMPHOGENOUS METASTASIS IN INVASIVE CARCINOMA OF NONSPECIFIC TYPE OF MAMMARY GLAND | 2016 |
|
RU2659938C2 |
METHOD FOR PREDICTION OF FULL REGRESSION PROBABILITY DURING NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH THREE-TIMES NEGATIVE MOLECULAR-GENETIC SUBTYPE OF BREAST CANCER | 2016 |
|
RU2623118C1 |
METHOD FOR PREDICTION OF DEGREE OF FULL REGRESSION PROBABILITY DURING NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH LUMINAL MOLECULAR-GENETIC SUBTYPE OF BREAST CANCER | 2016 |
|
RU2632112C1 |
METHOD FOR PREDICTION OF ONSET OF LOCAL RECURRENCES IN SURGICAL SCARS IN UNICENTRIC INVASIVE DUCT BREAST CANCER IN PATIENTS WITH PRESERVED MENSTRUAL FUNCTION | 2012 |
|
RU2486518C1 |
METHOD OF PREDICTING NODAL METASTASIS IN TWO-WAY SYNCHRONOUS INVASIVE CARCINOMA OF NON-SPECIFIC TYPE OF MAMMARY GLANDS | 2015 |
|
RU2578462C1 |
METHOD FOR HEMATOGENIC METASTASING PREDICTION IN CASE OF NON-SPECIFIC INVASIVE CARCINOMA OF BREAST IN PATIENTS WITH GOOD RESPONSE TO NEOADJUVANT CHEMOTHERAPY | 2016 |
|
RU2627649C1 |
METHOD FOR HEMATOGENOUS METASTASIS PREDICTION IN CASE OF NON-SPECIFIC INVASIVE BREAST CARCINOMA FOR PATIENTS WITH BAD RESPONSE TO NEOADJUVANT CHEMOTHERAPY | 2016 |
|
RU2623150C1 |
METHOD FOR PREDICTION OF HAEMATOGENIC METASTASIS IN DOUBLE-SIDED SYNCHRONOUS INVASIVE NON-SPECIFIC BREAST CARCINOMA | 2015 |
|
RU2589287C1 |
METHOD FOR PREDICTION OF COMPLETE MORPHOLOGICAL REGRESSIONS IN PATIENTS SUFFERING TRIPLE-NEGATIVE RESECTABLE BREAST CANCER | 2014 |
|
RU2560707C1 |
Authors
Dates
2015-08-10—Published
2014-03-28—Filed