FIELD: medicine, pharmaceutics.
SUBSTANCE: group of invention refers to ophthalmic compositions containing protease inhibition peptide substrates. The ophthalmic compositions contains a peptide substrate in a solution in the amount of approximately 0.01 wt/vol. % to 10 wt/vol. %, and said substrate is specified in a group consisting of gelatin, ovomacroglobulin, collagen and casein in an ophthalmically acceptable carrier. The composition additionally contains galactomannan and borate. The invention also describes a method for using the composition for treating dry eye.
EFFECT: group of invention provides higher viability and lower water loss of corneal epitheliocytes.
12 cl, 12 dwg, 11 ex
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Authors
Dates
2012-12-27—Published
2008-11-14—Filed