METHOD FOR RACEMATION OF OPTICALLY ACTIVE ALPHA-AMINOACETALS Russian patent published in 2012 - IPC C07C213/10 C07C217/40 C07C217/48 C07C249/04 C07B55/00 

Abstract RU 2470912 C2

FIELD: chemistry.

SUBSTANCE: invention relates to an improved method of producing α-aminoacetals of formula (I) in racemic form (I), where * denotes that the C atom is an asymmetric carbon, values of radicals R1-R6 are given in the claim, via racemation of optically rich α-aminoacetals of formula (R)-(I) or (S)-(I) The method involves a step for oxidation of an optically rich compound of formula (R)-(I) or (S)-(I), in the presence of a catalyst, to obtain an oxime of formula (II) and a step for reducing the compound of formula (II) to obtain a compound of formula (I) using a reducing agent.

EFFECT: method enables to obtain a product with high output under mild conditions.

15 cl, 4 ex

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RU 2 470 912 C2

Authors

Albala Mjuriel'

Primazo Zheral'Din

Vil'Ehl'M Did'E

Vallezho Zhan-Klod

Dates

2012-12-27Published

2008-05-21Filed