FIELD: chemistry.
SUBSTANCE: invention relates to an improved method of producing α-aminoacetals of formula (I) in racemic form (I), where * denotes that the C atom is an asymmetric carbon, values of radicals R1-R6 are given in the claim, via racemation of optically rich α-aminoacetals of formula (R)-(I) or (S)-(I) The method involves a step for oxidation of an optically rich compound of formula (R)-(I) or (S)-(I), in the presence of a catalyst, to obtain an oxime of formula (II) and a step for reducing the compound of formula (II) to obtain a compound of formula (I) using a reducing agent.
EFFECT: method enables to obtain a product with high output under mild conditions.
15 cl, 4 ex
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Authors
Dates
2012-12-27—Published
2008-05-21—Filed