COCRYSTALS Russian patent published in 2012 - IPC C07D239/42 A01N43/54 A01P3/00 

FIELD: chemistry.

SUBSTANCE: according to the present invention, cocrystals contain cyprodinil and a compound which forms cocrystals, which contains at least one organic acid functional group, where said compound which forms cocrystals is: a) benzoic acid. The cocrystal is characterised by X-ray powder diffraction pattern, expressed in 2 theta angle values, where the X-ray powder diffraction pattern includes 2 theta angle values of 11.201, 11.660, 13.78, 15.050, 18.584, 19.294, 20.793, 23.865, 25.697 and 26.765 and represents white rhomboid crystals. Alternatively, the compound which forms cocrystals is: b) amber acid. The cocrystal is characterised by X-ray powder diffraction pattern, expressed in 2 theta angle values, where the X-ray powder diffraction pattern includes 2 theta angle values of 12.5, 17.3, 18.7, 21.0, 22.4, 24.0, 25.4, 28.8 and 29.3. In said cocrystals, hydrogen bonds form between the compound which forms cocrystals and cyprodinil. The invention also relates to a method of producing cocrystals. The method involves a) grinding, heating or mixing cyprodinil and the compound which forms cocrystals in form of solutions under crystallisation conditions so that a solid phase forms; b) separating cocrystals containing cyprodinil and the compound which forms cocrystals. The invention also relates to a fungicide composition and a method of preventing/controlling fungal infections in plants. The method involves treating plants with a fungicidally effective amount of an agrochemical composition given in claim 4.

EFFECT: cocrystals have high stability and have activity which is comparable with that of other existing cyprodinil compositions.

5 cl, 24 dwg, 16 tbl