TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST VIRUS REPLICATION, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM Russian patent published in 2023 - IPC C07D403/14 A61K31/53 A61P31/14 

Abstract RU 2806042 C1

FIELD: medicine.

SUBSTANCE: invention is related to a compound represented by the formula

and its pharmaceutically acceptable salt. The invention is also related to a complex and a co-crystal containing said compound and fumaric acid in a 1:1 molar ratio, with an X-ray powder diffraction pattern having peaks at diffraction angles (2θ): 9.5±0.2°, 10.9±0.2°, 18.6±0.2°, 23.5±0.2° and 24.6±0.2°.

EFFECT: obtaining a new compound, as well as a complex and a co-crystal based on it with fumaric acid, which can be used in medicine for the treatment and/or prevention of a disease associated with coronavirus 3CL proteases.

12 cl, 13 dwg, 8 tbl, 6 ex

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RU 2 806 042 C1

Authors

Tachibana Yuki

Uehara Shota

Unoh Yuto

Nakahara Kenji

Taoda Yoshiyuki

Yamatsu Yukiko

Ando Shigeru

Sasaki Michihito

Dates

2023-10-25Published

2022-02-17Filed