FIELD: chemistry.
SUBSTANCE: present invention describes substituted amides which inhibit Btk. Described are pharmaceutical compositions containing at least one of the compounds along with at least one pharmaceutically acceptable medium selected from carriers, auxiliary components and filler materials. Described are methods of treating patients suffering from several diseases which are sensitive to inhibition of activity of Btk and/or activity of B-cells. Described are methods of determining presence of Btk in a sample.
EFFECT: improved method.
58 cl, 17 ex
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