OXADIAZOLE DERIVATIVES AND USE THEREOF AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS 842 Russian patent published in 2012 - IPC C07D413/14 A61K31/496 A61P25/00 

Abstract RU 2470931 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound which is 7-methyl-5-(3-piperazin-1-ylmethyl-[1,2,4]oxadiazol-5-yl)-2-(4-trifluoromethoxybenzyl)-2,3-dihydroisoindol-1-one, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition having potentiating activity on glutamate receptors, containing the compound described above; also described is use of the compound or a pharmaceutically acceptable salt in claim 1 in producing a medicinal agent for therapy of neurological and mental disorders associated with glutamate dysfunction.

EFFECT: novel compound which can be used in therapy of neurological and mental disorders is obtained and described.

5 cl, 4 ex

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RU 2 470 931 C2

Authors

Klehjton Dzhoshua

Ehgl Ajan

Ehmpfild Dzhejms

Folmer Dzhejms

Isaak Metvin

Ma Fupeng

Slassi Abdel'Malik

Dates

2012-12-27Published

2008-06-05Filed