FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to compounds of general formula 
and their pharmaceutically acceptable salts possessing the properties of TNFα inhibitor and IL-2 production stimulator, as well as to a pharmaceutical composition, a method of treating and a single standard dosage form and their use. In general formula, Y represents C=O or CH2; and R1 represents (C1-C6)alkyl substituted by (C1-C6)alkoxy group, 5-10-member aryl, (5-10-member aryl)-(C1-C6)alkyl, 5-10-member heterocyclyl, 5-10-member heterocyclyl-(C1-C6)alkyl, 5-10-member heteroaryl, (5-10-member heteroaryl)-(C1-C6)alkyl, (C1-C6)alkylcarbonyl, di(C1-C6)alkylaminocarbonyl, (C1-C6)alkoxycarbonyl, 5-10-member heteroarylcarbonyl or 5-10-member heterocyclylcarbonyl; wherein heterocyclyl contains 1-3 heteroatoms specified in N, S and O, and heteroaryl contains 1-3 heteroatoms specified in N, S and O and wherein R1 is optionally substituted by one or more groups specified in (C1-C6)alkoxy, halo, (C1-C6)alkyl, carboxy, (C1-C6)alkylaminocarbonyl and (C1-C6)alkoxycarbonyl.
EFFECT: preparing the pharmaceutically acceptable salts possessing the properties of TNFα inhibitor and IL-2 production stimulator.
23 cl, 1 tbl, 24 ex
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