FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology, particularly to obtaining a modified growth hormone, and can be used in medicine. By recombination, a polypeptide is obtained, which has antagonistic effect on the growth hormone receptor.
EFFECT: invention enables to obtain a polypeptide which is effective when treating conditions caused by excess growth hormone in the body of the patient.
11 cl, 19 dwg, 2 tbl
| Title |
Year |
Author |
Number |
| FUSED GROWTH HORMONE PROTEINS |
2008 |
- Ross Richard
- Artim'Juk Piter
- Sehjers Dzhon
|
RU2473554C2 |
| CHIMERIC POLYPEPTIDE - GROWTH HORMONE RECEPTOR ANTAGONIST, NUCLEIC ACID, EXPRESSION VECTOR, CHIMERIC POLYPEPTIDE APPLICATION (VERSIONS), PHARMACEUTICAL COMPOSITION, CELL, METHOD OF OBTAINING CHIMERIC POLYPEPTIDE AND METHOD OF TREATMENT |
2002 |
- Ross Richard
- Sehjers Dzhon
- Artim'Juk Piter
|
RU2346047C2 |
| COMBINED PROTEIN INHIBITING RECEPTOR SIGNAL TRANSMISSION OF HORMONE OF GROWTH (VERSIONS), METHOD OF ITS OBTAINING AND CLEARING AND PHARMACEUTICAL COMPOSITION ON ITS BASIS |
2002 |
|
RU2340628C2 |
| POLYPEPTIDE WITH GROWTH HORMONE RECEPTOR AGONIST PROPERTIES, NUCLEIC ACID CODING SAID POLYPEPTIDE, EXPRESSION VECTOR THEREOF AND CELL PRODUCING SAID POLYPEPTIDE |
2005 |
- Artimiuk Piter
- Pradkhananga Sarbendra
- Sehjers Dzhon
- Ross Richard
|
RU2391353C2 |
| NUCLEOTIDE AND AMINO ACID SEQUENCES OF OVICELL FACTORS FOR OVARY FOLLICLE GROWTH CHANGE IN VIVO OR IN VITRO |
2001 |
- Lajtinen Mika Petri Ehsajas
- Ritvos Olli Visa-Pekka
- Dehvis Dzhordzh Genri
- Gehllouehj S'Juzan Mehj
- Dzhuendzhel Dzhenni
- Maknehtti Kennet Pattrik
- Vuojolajnen Kaisa Niina Jokhanna
|
RU2270862C2 |
| CHIMERIC FIBROBLAST GROWTH FACTORS WITH CHANGED RECEPTOR SPECIFICITY |
2010 |
|
RU2573896C2 |
| HUMAN GROWTH HORMONE DERIVATIVE HIGHLY RESISTANT TO PROTEOLYTIC DEGRADATION, METHOD FOR PREPARING THIS DERIVATIVE, USING IT, METHOD OF TREATING, AND PHARMACEUTICAL COMPOSITION |
2010 |
- Olsen Ole Khvil'Sted
- Brajnkhol'T Jens
- S'Edt Kristine Bruun
- Demjut Khelle
- Nerskov-Lauritsen Leif
- Tjugesen Peter
|
RU2539797C2 |
| MESOTHELINE-TARGETED CANCER VACCINES AND THEIR APPLICATION |
2018 |
- Yan, Jian
- Slager, Anna
- Garman, Bradley
- Cooch, Neil
|
RU2751252C1 |
| CHIMERIC PROTEIN, A SYNTHETIC DNA WHICH CODES SAID PROTEIN, AN EXPRESSION VECTOR, A SYNTHETIC DNA PRODUCING STRAIN AND A METHOD OF PRODUCING PLASMID DNA |
2016 |
- Dukhovlinov Ilya Vladimirovich
|
RU2736472C2 |
| VIRUS-LIKE PARTICLES COMPOSITION |
2013 |
- Ueno Ryudzi
- Akakhata Vataru
|
RU2705301C2 |
