METHOD OF REDUCING INTRAOCULAR PRESSURE Russian patent published in 2013 - IPC A61F9/00 B82B3/00 A61K31/401 A61P27/06 

Abstract RU 2472471 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular, to ophthalmology and pharmacy, and is intended for reduction of intraocular pressure. Method includes introduction of specially elaborated medications from the group of angiotensin-converting enzyme into conjunctival cavity. Medication is characterised by the following: inhibitor is introduced in composition of calcium-phosphate biodegradable nanoparticles with radius 30-350 nm and in concentration 0.1% - 3%.

EFFECT: selection of nanoparticle size and corresponding concentration of said preparations, when they are introduced into conjunctival cavity, makes it possible to ensure enhance of prolongation of effect of intraocular pressure reduction with reduction of risk of local and general side effects, including application of prodrug forms of said inhibitors.

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RU 2 472 471 C1

Authors

Nikol'Skaja Irina Ivanovna

Shimanovskaja Ekaterina Viktorovna

Kost Ol'Ga Alekseevna

Chesnokova Natal'Ja Borisovna

Pavlenko Tat'Jana Arkad'Evna

Beznos Ol'Ga Valer'Evna

Binevskij Petr Vital'Evich

Kljachko Natal'Ja L'Vovna

Kabanov Aleksandr Viktorovich

Dates

2013-01-20Published

2011-11-24Filed