FIELD: medicine.
SUBSTANCE: invention is intended for treating eye diseases accompanied by oxidative stress. Superoxide dismutase is introduced into composition of calcium-phosphate biodegradable nanoparticles coated with disaccharide, with radius of up to 350 nm and in the range of enzymatic activity from 20 to 500 kunit/ml and is entered in eye's conjunctival cavity.
EFFECT: method enables higher therapeutic effectiveness of superoxide dismutase due to increased capacity of this enzyme to reduce intensity of oxidative stress in ophthalmic diseases.
1 cl, 6 ex
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Authors
Dates
2016-03-10—Published
2014-12-15—Filed