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(19)

(11)

2 472 804

(13)

(51)

IPC

C07K1/34(2006-01-01)

C07K14/745(2006-01-01)

C12N7/06(2006-01-01)

(21) (22)

Application

2006118024/10, 2004-12-01

(24)

Start date

2004-12-01

(22)

Actual filing date

2004-12-01

(45)

Published

2013-01-20

(72)

Inventor

Kristensen JesperKhalker EhrikPreuss TuridKhansen Tomas BuddeTomoda Lene Vehdele MadsenJokhansen Nina

(73)

Holder

Novo Nordisk Khels Kea Ag

METHOD OF REMOVING VIRUSES FROM LIQUID COMPOSITION CONTAINING FACTOR VII Russian patent published in 2013 - IPC C07K1/34 C07K14/745 C12N7/06

Abstract RU 2472804 C2

FIELD: chemistry.

SUBSTANCE: invention discloses versions of a method of cleaning a liquid composition which contains recombinant factor VII from viruses. The composition to be cleaned contains at least 5% recombinant polypeptide of factor VII in activated form. Cleaning is carried out using a nanofilter with pore size of at most 80 nm.

EFFECT: methods enable to obtain a clean recombinant polypeptide of factor VII without breakdown of its active form.

34 cl, 1 dwg, 6 ex

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RU 2 472 804 C2

Authors

Kristensen Jesper

Khalker Ehrik

Preuss Turid

Khansen Tomas Budde

Tomoda Lene Vehdele Madsen

Jokhansen Nina

Dates

2013-01-20—Published

2004-12-01—Filed