METHOD OF MANUFACTURING PHARMACEUTICAL PRODUCT, CONTAINING CITRIC ACID, MAGNESIUM OXIDE, POTASSIUM BICARBONATE AND SODIUM PICOSULFATE, PHARMACEUTICAL COMPOSITIONS, CONTAINING THUS OBTAINED GRANULES AND INTERMEDIATE COMPOUND Russian patent published in 2013 - IPC A61K9/16 A61K33/08 A61K31/194 A61P1/10 

Abstract RU 2473332 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to method of manufacturing compositions, containing potassium bicarbonate and sodium picosulfate, which includes stage of application by spraying sodium picosulfate solution on potassium bicarbonate and drying of said salts with formation of granules, containing sodium picosulfate layer on potassium bicarbonate core. Invention also relates to composition, suitable for obtaining composition, which possesses laxative action, which contains granules, including sodium picosulfate layer, applied on potassium bicarbonate core. Invention also relates to composition, possessing laxative action, and to method of its obtaining, which contains granules of homogeneous mixture of citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, and possibly sodium saccharin and/or orange flavouring agent, with granules containing sodium picosulfate, applied on potassium bicarbonate core.

EFFECT: invention is aimed at obtaining composition, which can be used for emptying of bowels before X-ray examination, endoscopy or surgery, which is homogeneous and possesses improved characteristics.

34 cl, 2 dwg, 3 ex

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RU 2 473 332 C2

Authors

Ksu Khajdzhun

D'Jao T'Edzhun

Dates

2013-01-27Published

2008-10-10Filed