LIQUID PHARMACEUTICAL COMPOSITION Russian patent published in 2018 - IPC A61K31/4425 A61K31/194 A61K33/08 A61K47/00 A61K9/08 A61P1/10 

Abstract RU 2668882 C2

FIELD: pharmaceuticals.

SUBSTANCE: composition contains sodium picosulphate, magnesium oxide, citric acid, malic acid and purified water in a weight ratio, respectively: (from 0.003 to 0.009) : (from 1 to 3) : (from 3.5 to 10.5) : (from 0.01 to 13) : 75, and an alkalizing agent in an amount necessary to adjust the pH of the pharmaceutical liquid composition in the range of 4.1 to 5.4. Alkalizing agent can be selected from the group consisting of sodium hydroxide, potassium hydroxide, sodium bicarbonate, ammonia solution, potassium citrate, triethanolamine and sodium citrate. In the composition of the invention, impurities of 2.0 % by weight are formed within 24 months or less, and no precipitate forms, or the precipitate is formed in an amount of 5.0 % by volume or less.

EFFECT: liquid pharmaceutical composition used as an agent for cleaning the colon, which is physically and chemically stable.

6 cl, 1 dwg, 4 tbl

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RU 2 668 882 C2

Authors

Nam Bon Gil

Li Bjeun Dzhun

Dzhin Sundzhi

Dates

2018-10-04Published

2014-06-23Filed